ABSTRACT
Background: Analysis of TIMI risk score & correlation with ST elevation myocardial infarction (STEMI). Methods: This is a 12 months Observational Cross- sectional study conducted at NIMS Medical College and Hospital- a tertiary hospital in rural areas close to Jaipur. In this study we included 60 patients with acute myocardial infarction who were admitted to the coronary care unit of NIMS HOSPITAL JAIPUR during the year JAN 2015 –DEC 2015. The data obtained were analysed using Excel sheet/SPSS software. Tests of significance were done using the Chi - square test at 95% confidence interval. Results: According to our study myocardial infarction was more common in male compared to female (male:female ratio 4:1) Complications rate is significantly higher in male patients(p=0.0010) compared to female patients(p=0.0114). Mortality is increased with the increase in TIMI risk score. Conclusion: TIMI Risk score for ST segment Elevation Myocardial Infarction (STEMI) may be readily applied at the bedside at the time of hospital presentation and captures the majority of prognostic information offered by a full logistic regression model. The mortality increased proportionally with TIMI score. This risk assessment tool is likely to be clinically useful in the triage and management of patients eligible for fibrinolytic therapy and may also serve as a valuable aid in clinical research. Sufficiently simple to be practical at the bedside and effective for risk assessment across a heterogeneous spectrum of patients, the TIMI risk score may be clinically useful in the triage and treatment of patients with STEMI who undergo acute reperfusion therapy.
ABSTRACT
Background: The objective of the study is to estimate platelet volume indices in patients of cerebral ischemic vascular disease. Methods: The present study was conducted on 170 subjects in Department of Medicine, NIMS Medical College and Hospital, Jaipur, Rajasthan over eighteen months. The study was conducted on 60 patients admitted in the wards and ICU under the Department of Medicine and 110 controls who were the normal and healthy during the study period. In this study the values of platelet indices – MPV, PDW and platelet count were observed in patients of cerebral ischemia. It was found that large platelets contribute to the prethrombotic state in ischemic syndromes and they may play a specific role in infarction. Because larger platelets are haemostatically more active and hence, their presence is probably a risk factor for developing thrombosis. Statistical analysis was done using Chi – square test, unpaired ‘t’ test and ANOVA test. A p value <0.05 was considered statistically significant. Results: In this study it was found that in cerebrovascular disease patients, MPV was 10.30±0.83 fL, PDW was 14.50±0.55 fL, platelet count was 260×109 ± 29×109 /L while in control, MPV was 8.14± 0.72 fL, PDW was 10.71±0.48 fL, platelet count was 285×109 ± 50 ×109 /L. MPV and PDW were higher and platelet count lower in cerebrovascular disease group and a highly significant difference (p<0.001) was found on comparing with controls. Conclusion: In this study, it was found that MPV and PDW were raised in cerebrovascular disease suggestive of statistically highly significant when compared to normal control group.